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Management of vitamin B12 deficiency in vegetarian patients

Vitamin B12 deficiency is a common concern, especially in vegetarian populations. This article addresses how nutritionists can identify, prevent, and manage this condition, providing practical information based on scientific evidence.

The role of vitamin B12 in health

Vitamin B12 (cobalamin) is essential for several biological functions, including red blood cell formation, DNA synthesis, and nervous system function. Its deficiency can lead to symptoms such as fatigue, megaloblastic anemia, and neurological damage.

Vegetarians, especially vegans, are at greater risk of deficiency due to the absence of food sources rich in B12 in their diets, such as meat, fish, and dairy products.

Identifying Vitamin B12 Deficiency

The diagnosis of vitamin B12 deficiency involves:

  1. Clinical assessment: Symptoms such as tiredness, tingling in the extremities, and difficulty concentrating are indicative.
  1. Laboratory tests: Serum vitamin B12 levels below 200 pg/mL generally suggest deficiency. Other tests, such as methylmalonic acid and homocysteine, may help confirm the condition.

Detailed analysis of the patient's dietary history is also important to determine the risk.

Main strategies for the management of deficiency in vegetarians

  1. Dietary education and preventive supplementation

Dietary education is one of the most important tools in controlling vitamin B12 deficiency. The nutritionist should advise vegetarian patients on the importance of including fortified foods and supplements in the routine.

  • Fortified foods: Cereals, plant-based milks, and nutritional yeast are good options.
  • Oral supplementation: It is indicated for vegetarians at risk of deficiency. The dosage varies according to the patient's needs, but doses of 500 to 1000 mcg daily are generally effective.

  1. Treatment of confirmed disability

For patients with a diagnosed disability, treatment may include:

  • Oral supplementation: Higher doses, such as 2000 mcg daily, may be indicated initially.
  • Intramuscular injections: In severe cases, doses of 1000 mcg are administered weekly until serum levels normalize, followed by monthly doses.

  1. Regular monitoring

After starting supplementation, it is essential to reevaluate vitamin B12 levels and associated markers (methylmalonic acid and homocysteine) at regular intervals to ensure efficacy and adjust doses as necessary.

Vitamin B12 supplementation: myths and truths

A common question among vegetarians is whether regular supplementation is really necessary. Research confirms that, even with a well-planned diet, it's difficult to meet daily vitamin B12 requirements with fortified foods alone.

In addition, it is important to clarify that:

  • There are no significant risks of overdosing, as the body eliminates excess vitamin B12 through the urine. This makes supplementation safe, even at high doses, especially for populations at higher risk of deficiency.
  • Fermented or organic foods are not reliable sources of vitamin B12. Studies show that the bioavailability of B12 in these foods is limited, and relying on them alone may increase the risk of deficiency.
  • Regular supplementation is recommended even without apparent symptoms. B12 deficiency can be subclinical for a long period, with long-term negative impact, such as irreversible neurological impairment.

By demystifying these points, the nutritionist can provide patients with more assertive information, reinforcing the importance of supplementation for vegetarians, especially vegans.

How to customize management for different vegetarian profiles

Not all vegetarians have the same level of risk. It is necessary to individualize the management plan:

  • Ovolactovegetarians: They generally have a lower risk, but the intake of dairy products and eggs should be evaluated.
  • Vegans: These require mandatory supplementation due to the complete absence of natural food sources of vitamin B12.

Regular dietary history assessment helps nutritionists adjust preventive or therapeutic management.

Long-term prevention

To ensure the health of vegetarian patients, the nutritionist must:

  • Establish a realistic and sustainable eating plan, including fortified foods.
  • Reinforce adherence to the use of supplements, with clear dosage guidelines.
  • Create an annual follow-up routine, even for patients with no apparent symptoms.

Conclusion

Vitamin B12 deficiency in vegetarians can be prevented and managed with well-designed strategies. The nutritionist's role is essential in early identification, prevention and personalized treatment. With evidence-based guidance and adequate monitoring, it is possible to ensure the health and well-being of vegetarian patients.

WHEN/WHERE
18
Feb
Vitafor Science
18
/
02
/
2025
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